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CHSY1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q86X52
Clone Names 100406065
Peptide ID 100406065
Additional Information
Gene ID 22856
Other Names Chondroitin sulfate synthase 1, Chondroitin glucuronyltransferase 1, Chondroitin synthase 1, ChSy-1, Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1, N-acetylgalactosaminyltransferase 1, CHSY1, CHSY, CSS1, KIAA0990
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13586c was selected from the Center region of CHSY1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CHSY1
Synonyms CHSY, CSS1, KIAA0990
Function Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
Cellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein Secreted
Tissue Location Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes.
Research Areas
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CHSY1 synthesizes chondroitin sulfate, a glycosaminoglycanexpressed on the surface of most cells and in extracellularmatrices. Glycosaminoglycan chains are covalently linked to a widerange of core protein families and regulate many biologicprocesses, including cell proliferation and recognition,extracellular matrix deposition, and morphogenesis.[supplied byOMIM].


Yada, T., et al. J. Biol. Chem. 278(41):39711-39725(2003)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Kitagawa, H., et al. J. Biol. Chem. 278(26):23666-23671(2003)Kitagawa, H., et al. J. Biol. Chem. 276(42):38721-38726(2001)

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$ 80.00
Cat# BP13586c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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