|Other Names||Xin actin-binding repeat-containing protein 1, Cardiomyopathy-associated protein 1, XIRP1, CMYA1, XIN|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13612b was selected from the C-term region of XIRP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Protects actin filaments from depolymerization.|
|Cellular Location||Cell junction. Note=Colocalizes with actin stress fibers|
|Tissue Location||Isoform A, isoform B and isoform C are expressed in heart.|
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Provided below are standard protocols that you may find useful for product applications.
XIRP1 protects actin filaments from depolymerization.
Claeys, K.G., et al. Acta Neuropathol. 117(3):293-307(2009)van der Ven, P.F., et al. Exp. Cell Res. 312(11):2154-2167(2006)Pacholsky, D., et al. J. Cell. Sci. 117 (PT 22), 5257-5268 (2004) :Sinn, H.W., et al. Dev. Dyn. 225(1):1-13(2002)Wang, D.Z., et al. Development 126(6):1281-1294(1999)
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