|Other Names||Modulator of retrovirus infection homolog, MRI, C7orf49|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13615a was selected from the N-term region of C7orf49. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May participate in the non-homologous end joining pathway of DNA double-strand break (DSB) repair (PubMed:24610814). May act as a regulator of proteasome (By similarity).|
|Cellular Location||Isoform 1: Cytoplasm. Nucleus. Note=Nuclear localization may depend upon interaction with XRCC5/Ku80 and XRCC6/Ku70 heterodimer. Isoform 4: Cytoplasm. Nucleus. Note=Nuclear localization may depend upon interaction with XRCC5/Ku80 and XRCC6/Ku70 heterodimer and increases upon etoposide treatment|
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Provided below are standard protocols that you may find useful for product applications.
C7orf49 may act as a regulator of proteasome (By similarity).
Agarwal, S., et al. Proc. Natl. Acad. Sci. U.S.A. 103(43):15933-15938(2006)
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