|Other Names||Testis-expressed sequence 11 protein, TEX11|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13616c was selected from the Center region of TEX11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers (By similarity).|
|Cellular Location||Chromosome. Note=Forms arrays of discrete foci along synaptonemal complexes in spermatocytes and fetal oocytes.|
|Tissue Location||Testis-specific. Not expressed in adult ovaries.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is X-linked and is expressed in only male germcells. Two alternatively spliced transcript variants encodingdistinct isoforms have been found for this gene. [provided byRefSeq].
Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)Lim, J., et al. Cell 125(4):801-814(2006)Wang, P.J., et al. Nat. Genet. 27(4):422-426(2001)
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