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ADAL Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6DHV7
Clone Names 100408044
Additional Information
Gene ID 161823
Other Names Adenosine deaminase-like protein, 354-, ADAL
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13621b was selected from the C-term region of ADAL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADAL
Synonyms ADAL1 {ECO:0000303|PubMed:21755941}
Function Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine (PubMed:21755941, PubMed:29884623). Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A) (PubMed:21755941, PubMed:29884623). Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro (PubMed:21755941).
Research Areas
Citations (0)
citation

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Background

ADAL is a putative nucleoside deaminase. It may catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity).

References

Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)

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$ 277.78
Cat# BP13621b
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