ADAL Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6DHV7 |
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Clone Names | 100408044 |
Gene ID | 161823 |
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Other Names | Adenosine deaminase-like protein, 354-, ADAL |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13621b was selected from the C-term region of ADAL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ADAL |
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Synonyms | ADAL1 {ECO:0000303|PubMed:21755941} |
Function | Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine (PubMed:21755941, PubMed:29884623). Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A) (PubMed:21755941, PubMed:29884623). Catalyzes the removal of different alkyl groups not only from N6-substituted purine or 2-aminopurine nucleoside monophosphates but also from O6-substituted compounds in vitro (PubMed:21755941). |
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Provided below are standard protocols that you may find useful for product applications.
Background
ADAL is a putative nucleoside deaminase. It may catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity).
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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