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DOLPP1 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q86YN1
Clone Names 100416050
Peptide ID 100416050
Additional Information
Gene ID 57171
Other Names Dolichyldiphosphatase 1, Dolichyl pyrophosphate phosphatase 1, DOLPP1, LSFR2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13656b was selected from the C-term region of DOLPP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DOLPP1
Synonyms LSFR2
Function Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Background

DOLPP1 is required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity).

References

Humphray, S.J., et al. Nature 429(6990):369-374(2004)Rush, J.S., et al. J. Biol. Chem. 277(47):45226-45234(2002)Gilley, J., et al. Hum. Mol. Genet. 8(7):1313-1320(1999)Wedgwood, J.F., et al. J. Biol. Chem. 255(3):1120-1123(1980)

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$ 80.00
Cat# BP13656b
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