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ITGAL Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P20701
Clone Names 100427017
Peptide ID 100427017
Additional Information
Gene ID 3683
Other Names Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD11a, ITGAL, CD11A
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13692c was selected from the Center region of ITGAL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD11A
Function Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Leukocytes.
Research Areas
Citations (0)

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ITGAL encodes the integrin alpha L chain. Integrins areheterodimeric integral membrane proteins composed of an alpha chainand a beta chain. This I-domain containing alpha integrin combineswith the beta 2 chain (ITGB2) to form the integrin lymphocytefunction-associated antigen-1 (LFA-1), which is expressed on allleukocytes. LFA-1 plays a central role in leukocyte intercellularadhesion through interactions with its ligands, ICAMs 1-3(intercellular adhesion molecules 1 through 3), and also functionsin lymphocyte costimulatory signaling. Two transcript variantsencoding different isoforms have been found for this gene.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Kuwano, Y., et al. Blood 116(4):617-624(2010)Ghannam, S., et al. J. Immunol. 185(1):302-312(2010)Quist, S.R., et al. Acta Derm. Venereol. 90(4):429-430(2010)Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)

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$ 80.00
Cat# BP13692c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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