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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   SLC11A2 Antibody (Center) Blocking peptide   

SLC11A2 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P49281
Clone Names 100525166
Peptide ID 100525166
Additional Information
Gene ID 4891
Other Names Natural resistance-associated macrophage protein 2, NRAMP 2, Divalent cation transporter 1, Divalent metal transporter 1, DMT-1, Solute carrier family 11 member 2, SLC11A2, DCT1, DMT1, NRAMP2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13801c was selected from the Center region of SLC11A2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC11A2
Synonyms DCT1, DMT1, NRAMP2
Function Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
Cellular Location Isoform 2: Cell membrane; Multi- pass membrane protein. Early endosome
Tissue Location Ubiquitously expressed. Isoform 1 is highly expressed in brain. Isoform 2 is highly expressed in spleen, thymus and pancreas. Isoform 3 and isoform 4 are abundantly expressed in duodenum and kidney.
Research Areas
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This gene encodes a member of the solute carrier family 11protein family. The product of this gene transports divalent metalsand is involved in iron absorption. Mutations in this gene areassociated with hypochromic microcytic anemia with iron overload. Arelated solute carrier family 11 protein gene is located onchromosome 2. Multiple transcript variants encoding differentisoforms have been found for this gene.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Tabuchi, M., et al. J. Cell. Sci. 123 (PT 5), 756-766 (2010) :Tabuchi, M., et al. Mol. Biol. Cell 13(12):4371-4387(2002)

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$ 80.00
Cat# BP13801c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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