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RAB1B Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9H0U4
Clone Names 100318142
Peptide ID 100318142
Additional Information
Gene ID 81876
Other Names Ras-related protein Rab-1B, RAB1B
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13810b was selected from the C-term region of RAB1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB1B
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.
Cellular Location Cytoplasm. Membrane; Lipid-anchor; Cytoplasmic side. Preautophagosomal structure membrane; Lipid-anchor; Cytoplasmic side. Note=Targeted by REP1 to membranes of specific subcellular compartments including endoplasmic reticulum, Golgi apparatus, and intermediate vesicles between these two compartments. In the GDP-form, colocalizes with GDI in the cytoplasm (By similarity).
Research Areas
Citations (0)

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Members of the RAB protein family, such as RAB1B, are lowmolecular mass monomeric GTPases localized on the cytoplasmicsurfaces of distinct membrane-bound organelles. RAB1B functions inthe early secretory pathway and is essential for vesicle transportbetween the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997[PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[suppliedby OMIM].


Yamayoshi, S., et al. J. Virol. 84(9):4816-4820(2010)Machner, M.P., et al. Science 318(5852):974-977(2007)Monetta, P., et al. Mol. Biol. Cell 18(7):2400-2410(2007)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

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$ 80.00
Cat# BP13810b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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