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CASP6 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P55212
Clone Names 100427053
Peptide ID 100427053
Additional Information
Gene ID 839
Other Names Caspase-6, CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11, CASP6, MCH2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13835a was selected from the N-term region of CASP6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CASP6
Synonyms MCH2
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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This gene encodes a protein which is a member of thecysteine-aspartic acid protease (caspase) family. Sequentialactivation of caspases plays a central role in the execution-phaseof cell apoptosis. Caspases exist as inactive proenzymes whichundergo proteolytic processing at conserved aspartic residues toproduce two subunits, large and small, that dimerize to form theactive enzyme. This protein is processed by caspases 7, 8 and 10,and is thought to function as a downstream enzyme in the caspaseactivation cascade. Alternative splicing of this gene results intwo transcript variants that encode different isoforms. [providedby RefSeq].


Wurstle, M.L., et al. J. Biol. Chem. 285(43):33209-33218(2010)Lee, S.Y., et al. J Thorac Oncol 5(8):1152-1158(2010)Halawani, D., et al. J. Neurosci. 30(17):6132-6142(2010)Kim, M.S., et al. APMIS 118(4):308-312(2010)Yoo, N.J., et al. Tumori 96(1):138-142(2010)

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$ 80.00
Cat# BP13835a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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