|Other Names||Ras-related protein Rab-6B, RAB6B|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13850b was selected from the C-term region of RAB6B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.|
|Cellular Location||Golgi apparatus membrane; Lipid- anchor. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle. Note=Colocalizes with BICD1 at vesicular structures that align along microtubules|
|Tissue Location||Predominantly expressed in brain.|
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RAB6B seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Rose, J. Phd, et al. Mol. Med. (2010) In press :Wanschers, B., et al. Cell Motil. Cytoskeleton 65(3):183-196(2008)Wanschers, B.F., et al. Exp. Cell Res. 313(16):3408-3420(2007)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Garcia-Saez, I., et al. Acta Crystallogr. D Biol. Crystallogr. 62 (PT 7), 725-733 (2006) :
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