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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   SLC24A2 Antibody (Center) Blocking peptide   

SLC24A2 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9UI40
Clone Names 100324164
Peptide ID 100324164
Additional Information
Gene ID 25769
Other Names Sodium/potassium/calcium exchanger 2, Na(+)/K(+)/Ca(2+)-exchange protein 2, Retinal cone Na-Ca+K exchanger, Solute carrier family 24 member 2, SLC24A2, NCKX2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13886c was selected from the Center region of SLC24A2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC24A2
Synonyms NCKX2
Function Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Cellular Location Membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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The outer segment of retinal rod and cone photoreceptorscontains electrogenic sodium-calcium exchangers which mediate alight-induced decrease in free calcium concentration. This functionin cones is performed by SLC24A2 (Prinsen et al., 2000 [PubMed10662833]).


Altimimi, H.F., et al. J. Biol. Chem. 285(20):15245-15255(2010)Trynka, G., et al. Gut 58(8):1078-1083(2009)Kim, S.H., et al. Clin. Exp. Allergy 39(2):203-212(2009)Ginger, R.S., et al. J. Biol. Chem. 283(9):5486-5495(2008)Altimimi, H.F., et al. J. Biol. Chem. 282(6):3720-3729(2007)

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$ 80.00
Cat# BP13886c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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