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Mouse Mylk3 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q3UIZ8
Clone Names 110316281
Peptide ID 110316281
Additional Information
Gene ID 213435
Other Names Myosin light chain kinase 3, Cardiac-MyBP-C-associated Ca/CaM kinase, Cardiac-MLCK, Mylk3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13923a was selected from the N-term region of Mouse Mylk3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mylk3
Function Kinase that phosphorylates MYL2 in vitro. Has been proposed to be calmodulin-dependent (PubMed:17885681), although MYL2 phosphorylation has also been observed in the presence or absence of calmodulin (PubMed:18202317). Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility.
Cellular Location Cytoplasm.
Tissue Location Restricted to cardiomyocytes (at protein level). Down-regulated in heart after experimental myocardial infarction at the protein level; no significant changes at the mRNA level.
Research Areas
Citations (0)

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Mylk3 may play a role in smooth muscle contraction (By similarity).


White, R.A., et al. Blood Cells Mol. Dis. 43(2):141-148(2009)Chan, J.Y., et al. Circ. Res. 102(5):571-580(2008)Kim, B.J., et al. Can. J. Physiol. Pharmacol. 85(12):1254-1262(2007)Seguchi, O., et al. J. Clin. Invest. 117(10):2812-2824(2007)Choi, Y.O., et al. Exp. Mol. Med. 38(2):180-189(2006)

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$ 80.00
Cat# BP13923a
Availability: In Stock
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