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PNPLA4 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P41247 |
|---|---|
| Clone Names | 100405057 |
| Gene ID | 8228 |
|---|---|
| Other Names | Patatin-like phospholipase domain-containing protein 4, Protein GS2, PNPLA4, DXS1283E, GS2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13971b was selected from the C-term region of PNPLA4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PNPLA4 (HGNC:24887) |
|---|---|
| Function | Has abundant triacylglycerol lipase activity (PubMed:15364929, PubMed:16150821, PubMed:17603008). Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides (PubMed:17603008). Additionally possesses acylglycerol transacylase and phospholipase A2 activities (PubMed:15364929, PubMed:17603008). |
| Cellular Location | Mitochondrion. |
| Tissue Location | Expressed in all tissues examined, including heart, brain, placenta, lung, liver, muscle, kidney, pancreas and spleen |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the patatin-like family ofphospholipases. The encoded enzyme has both triacylglycerol lipaseand transacylase activities and may be involved in adipocytetriglyceride homeostasis. Alternate splicing results in multipletranscript variants. A pseudogene of this gene is found onchromosome Y.
References
Gao, J.G., et al. Mol. Genet. Metab. 96(4):253-260(2009)Kienesberger, P.C., et al. J. Lipid Res. 50 SUPPL, S63-S68 (2009) :Johansson, L.E., et al. PLoS ONE 4 (4), E5327 (2009) :Gao, J.G., et al. Biochem. Biophys. Res. Commun. 360(2):501-506(2007)Wilson, P.A., et al. J. Lipid Res. 47(9):1940-1949(2006)
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