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CD163L1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NR16 |
|---|---|
| Clone Names | 100416090 |
| Gene ID | 283316 |
|---|---|
| Other Names | Scavenger receptor cysteine-rich type 1 protein M160, CD163 antigen-like 1, CD163b, CD163L1, CD163B, M160 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13979b was selected from the C-term region of CD163L1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CD163L1 |
|---|---|
| Synonyms | CD163B, M160 |
| Cellular Location | [Isoform 1]: Cell membrane; Single- pass type I membrane protein [Isoform 3]: Secreted. |
| Tissue Location | Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines Isoform 2 is only expressed in spleen. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the scavenger receptorcysteine-rich (SRCR) superfamily. Members of this family aresecreted or membrane-anchored proteins mainly found in cellsassociated with the immune system. The SRCR family is defined by a100-110 amino acid SRCR domain, which may mediate protein-proteininteraction and ligand binding. The encoded protein contains twelveSRCR domains, a transmembrane region and a cytoplasmic domain.Alternatively spliced transcript variants encoding differentisoforms have been described but their full-length nature has notbeen determined.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Davila, S., et al. Genes Immun. 11(3):232-238(2010)Van Gorp, H., et al. J. Virol. 84(6):3101-3105(2010)Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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