|Other Names||Integrin beta-5, ITGB5|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14000a was selected from the N-term region of ITGB5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Li, Z., et al. J. Biol. Chem. 285(31):23699-23710(2010)Leifheit-Nestler, M., et al. Arterioscler. Thromb. Vasc. Biol. 30(7):1398-1406(2010)Lane, D., et al. Oncogene 29(24):3519-3531(2010)Lyle, C., et al. Virol. J. 7, 148 (2010) :
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