Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   RFX5 Antibody (Center) Blocking peptide   

RFX5 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P48382
Clone Names 100427305
Peptide ID 100427305
Additional Information
Gene ID 5993
Other Names DNA-binding protein RFX5, Regulatory factor X 5, RFX5
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14004c was selected from the Center region of RFX5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RFX5
Function Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.
Cellular Location Nucleus.
Tissue Location Ubiquitous.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


A lack of MHC-II expression results in a severeimmunodeficiency syndrome called MHC-II deficiency, or the barelymphocyte syndrome (BLS; MIM 209920). At least 4 complementationgroups have been identified in B-cell lines established frompatients with BLS. The molecular defects in complementation groupsB, C, and D all lead to a deficiency in RFX, a nuclear proteincomplex that binds to the X box of MHC-II promoters. The lack ofRFX binding activity in complementation group C results frommutations in the RFX5 gene encoding the 75-kD subunit of RFX(Steimle et al., 1995). RFX5 is the fifth member of the growingfamily of DNA-binding proteins sharing a novel and highlycharacteristic DNA-binding domain called the RFX motif. Multiplealternatively spliced transcript variants have been found but thefull-length natures of only two have been determined. [provided byRefSeq].


Laird, K.M., et al. J. Mol. Biol. 403(1):40-51(2010)Kong, X., et al. J. Mol. Cell. Cardiol. 46(3):292-299(2009)Garvie, C.W., et al. Biochim. Biophys. Acta 1779(12):797-804(2008)Ennis, S., et al. Lancet 372(9652):1828-1834(2008)Xu, Y., et al. J. Biol. Chem. 282(36):26046-26056(2007)

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 80.00
Cat# BP14004c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions