|Other Names||Vesicular acetylcholine transporter, VAChT, Solute carrier family 18 member 3, SLC18A3, VACHT|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14010c was selected from the Center region of SLC18A3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in acetylcholine transport into synaptic vesicles.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Peripheral and central cholinergic nervous systems.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the vesicular amine transporterfamily. The encoded transmembrane protein transports acetylcholineinto secretory vesicles for release into the extracellular space.Acetylcholine transport utilizes a proton gradient established by avacuolar ATPase. This gene is located within the first intron ofthe choline acetyltransferase gene.
Khare, P., et al. J. Neurochem. 115(4):984-993(2010)Harrington, A.M., et al. Cell Tissue Res. 341(1):33-48(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)Khare, P., et al. Biochemistry 48(38):8965-8975(2009)
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