Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
AVPR1B Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P47901 |
|---|---|
| Clone Names | 100507026 |
| Gene ID | 553 |
|---|---|
| Other Names | Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, AVPR1B, AVPR3, VPR3 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP14050b was selected from the C-term region of AVPR1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AVPR1B (HGNC:896) |
|---|---|
| Synonyms | AVPR3, VPR3 |
| Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene acts as receptor forarginine vasopressin. This receptor belongs to the subfamily ofG-protein coupled receptors which includes AVPR1A, V2R and OXTreceptors. Its activity is mediated by G proteins which stimulate aphosphatidylinositol-calcium second messenger system. The receptoris primarily located in the anterior pituitary, where it stimulatesACTH release. It is expressed at high levels in ACTH-secretingpituitary adenomas as well as in bronchial carcinoids responsiblefor the ectopic ACTH syndrome. A spliced antisense transcript ofthis gene has been reported but its function is not known.
References
van West, D., et al. Psychiatry Res 179(1):64-68(2010)Binder, E.B., et al. Arch. Gen. Psychiatry 67(4):369-379(2010)Bosker, F.J., et al. Mol. Psychiatry (2010) In press :van West, D., et al. Psychiatr. Genet. 19(2):102-103(2009)Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
