Mouse Mst4 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q99JT2 |
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Clone Names | 110316278 |
Gene ID | 70415 |
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Other Names | Serine/threonine-protein kinase 26, Stk26 {ECO:0000312|MGI:MGI:1917665} |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP14072c was selected from the Center region of Mouse Mst4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Stk26 {ECO:0000312|MGI:MGI:1917665} |
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Function | Serine/threonine-protein kinase that acts as a mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation. Phosphorylates ATG4B at 'Ser-383', thereby increasing autophagic flux. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q9P289}. Golgi apparatus {ECO:0000250|UniProtKB:Q9P289}. Note=Colocalized with RIPOR1 in the Golgi of serum-starved cells and relocated to cytoplasmic punctae, probably vesicular compartments, along with RIPOR1 upon serum stimulation in a Rho- and PDCD10-dependent manner {ECO:0000250|UniProtKB:Q9P289} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Mediator of cell growth. Modulates apoptosis (By similarity).
References
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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