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Mouse Npr1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P18293
Clone Names 110316298
Peptide ID 110316298
Additional Information
Gene ID 18160
Other Names Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor type A, ANP-A, ANPR-A, NPR-A, Guanylate cyclase A, GC-A, Npr1, Npra
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14073a was selected from the N-term region of Mouse Npr1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Npr1
Synonyms Npra
Function Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.

References

Madhani, M., et al. Am. J. Physiol. Heart Circ. Physiol. 299 (3), H827-H836 (2010) :Panayiotou, C.M., et al. Br. J. Pharmacol. 160(8):2045-2054(2010)Ropero, A.B., et al. Endocrinology 151(8):3665-3674(2010)Tankersley, C.G., et al. Inhal Toxicol 22(8):695-707(2010)Long, L., et al. Neuro Endocrinol. Lett. 31(1):126-130(2010)

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$ 80.00
Cat# BP14073a
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