|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14093a was selected from the N-term region of KRT10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the type I (acidic)cytokeratin family, which belongs to the superfamily ofintermediate filament (IF) proteins. Keratins are heteropolymericstructural proteins which form the intermediate filament. Thesefilaments, along with actin microfilaments and microtubules,compose the cytoskeleton of epithelial cells. Mutations in thisgene are associated with epidermolytic hyperkeratosis. This gene islocated within a cluster of keratin family members on chromosome17q21.
Choate, K.A., et al. Science 330(6000):94-97(2010)Xiao, J., et al. Pancreas 39 (1), E17-E23 (2010) :Terheyden, P., et al. J. Invest. Dermatol. 129(11):2721-2723(2009)Jacques, C.M., et al. J Oral Sci 51(3):355-365(2009)Barcelos, A.C., et al. J. Cutan. Pathol. 36(6):647-654(2009)
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