|Other Names||Copper chaperone for superoxide dismutase, Superoxide dismutase copper chaperone, CCS|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14113c was selected from the Center region of CCS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Delivers copper to copper zinc superoxide dismutase (SOD1).|
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Provided below are standard protocols that you may find useful for product applications.
Copper chaperone for superoxide dismutase specificallydelivers Cu to copper/zinc superoxide dismutase and may activatecopper/zinc superoxide dismutase through direct insertion of the Cucofactor.
Brady, G.F., et al. Mol. Cell. Biol. 30(8):1923-1936(2010)Winkler, D.D., et al. Biochemistry 48(15):3436-3447(2009)Barry, A.N., et al. Biochemistry 47(49):13074-13083(2008)Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)Furukawa, Y., et al. J. Biol. Chem. 283(35):24167-24176(2008)
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