|Other Names||Casein kinase I isoform gamma-1, CKI-gamma 1, Csnk1g1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14134b was selected from the C-term region of Mouse Csnk1g1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CLSPN (By similarity). Regulates fast synaptic transmission mediated by glutamate.|
|Tissue Location||Expressed in both the striatum and the neocortex.|
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Provided below are standard protocols that you may find useful for product applications.
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity).
Chergui, K., et al. J. Neurosci. 25(28):6601-6609(2005)Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)Stryke, D., et al. Nucleic Acids Res. 31(1):278-281(2003)Fujimoto, S., et al. Nucleic Acids Res. 21 (18), 4403 (1993) :
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