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UBP46 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P62068
Clone Names 110330014
Peptide ID 110330014
Additional Information
Gene ID 64854
Other Names Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46, USP46
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14161b was selected from the C-term region of UBP46. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name USP46
Function Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
Tissue Location Broadly expressed.
Research Areas
Citations (0)

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Modification of cellular proteins by ubiquitin is anessential regulatory mechanism controlled by the coordinated actionof multiple ubiquitin-conjugating and deubiquitinating enzymes.USP46 belongs to a large family of cysteine proteases that functionas deubiquitinating enzymes (Quesada et al., 2004 [PubMed14715245]).


Kushima, I., et al. J. Hum. Genet. 55(3):133-136(2010)Cohn, M.A., et al. J. Biol. Chem. 284(8):5343-5351(2009)Zemunik, T., et al. Croat. Med. J. 50(1):23-33(2009)Quesada, V., et al. Biochem. Biophys. Res. Commun. 314(1):54-62(2004)Puente, X.S., et al. Nat. Rev. Genet. 4(7):544-558(2003)

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$ 80.00
Cat# BP14161b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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