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PRSS8 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16651
Clone Names 100507010
Peptide ID 100507010
Additional Information
Gene ID 5652
Other Names Prostasin, 3421-, Channel-activating protease 1, CAP1, Serine protease 8, Prostasin light chain, Prostasin heavy chain, PRSS8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRSS8
Function Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
Cellular Location Prostasin: Cell membrane; Single-pass membrane protein Prostasin heavy chain: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus
Tissue Location Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid
Research Areas
Citations (0)

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This gene encodes a trypsinogen, which is a member of thetrypsin family of serine proteases. This enzyme is highly expressedin prostate epithelia and is one of several proteolytic enzymesfound in seminal fluid. The proprotein is cleaved to produce alight chain and a heavy chain which are associated by a disulfidebond. It is active on peptide linkages involving the carboxyl groupof lysine or arginine.


Chen, Y.W., et al. J. Biol. Chem. 285(41):31755-31762(2010)Chen, M., et al. Mol. Cell. Biochem. 337 (1-2), 259-266 (2010) :Fu, Y.Y., et al. Hum. Reprod. 25(3):623-632(2010)Ko, T., et al. J. Biomed. Biotechnol. 2010, 793843 (2010) :Chang, J.H., et al. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 31(6):712-719(2009)

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$ 80.00
Cat# BP14207c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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