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SESTD1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q86VW0
Clone Names 91218147
Peptide ID 91218147
Additional Information
Gene ID 91404
Other Names SEC14 domain and spectrin repeat-containing protein 1, Huntingtin-interacting protein-like protein, Protein Solo, SESTD1, SOLO
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SESTD1
Synonyms SOLO
Function May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.
Tissue Location Broad expression. High expression in thalamus and brain. Significantly expressed in vasculature
Research Areas
Citations (0)

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Background

SESTD1 may act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Miehe, S., et al. J. Biol. Chem. 285(16):12426-12434(2010)Trynka, G., et al. Gut 58(8):1078-1083(2009)Sato, T., et al. Genomics 82(2):218-229(2003)

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$ 80.00
Cat# BP14214a
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