|Other Names||Dihydropyrimidinase-related protein 3, DRP-3, Collapsin response mediator protein 4, CRMP-4, Unc-33-like phosphoprotein 1, ULIP-1, DPYSL3, CRMP4, DRP3, ULIP, ULIP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CRMP4, DRP3, ULIP, ULIP1|
|Function||Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).|
|Cellular Location||Cytoplasm. Cell projection, growth cone. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.|
|Tissue Location||Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord|
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Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
Okita, K., et al. Cancer Sci. 101(11):2333-2340(2010)Gao, X., et al. Oncogene 29(32):4555-4566(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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