|Other Names||MAP/microtubule affinity-regulating kinase 3, ELKL motif kinase 2, EMK-2, MPK-10, Mark3, Emk2, Mpk10|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the specific phosphorylation of microtubule- associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (By similarity).|
|Cellular Location||Cell membrane; Peripheral membrane protein|
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Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C (By similarity).
Lennerz, J.K., et al. Mol. Cell. Biol. 30(21):5043-5056(2010)Schwarz, T., et al. Biochem. Biophys. Res. Commun. 394(4):890-895(2010)Hezel, A.F., et al. Mol. Cell. Biol. 28(7):2414-2425(2008)Wang, C., et al. Acta Pharmacol. Sin. 28(3):334-338(2007)Tochio, N., et al. Protein Sci. 15(11):2534-2543(2006)
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