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Mouse Matk Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P41242
Clone Names 110316266
Peptide ID 110316266
Additional Information
Gene ID 17179
Other Names Megakaryocyte-associated tyrosine-protein kinase, Protein kinase NTK, Tyrosine-protein kinase CTK, Matk, Ctk, Ntk
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Matk
Synonyms Ctk, Ntk
Function Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
Cellular Location Cytoplasm. Membrane. Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
Tissue Location Most abundant in brain, and to a lesser extent in the spleen, the thymus and the liver. Also found in the T-cell lineage
Research Areas
Citations (0)

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Background

Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.

References

Lee, B.C., et al. Blood 108(3):904-907(2006)Robinson, D.R., et al. Oncogene 19(49):5548-5557(2000)Puttagunta, R., et al. Genome Res. 10(9):1369-1380(2000)Samokhvalov, I., et al. Biochem. Mol. Biol. Int. 43(1):115-122(1997)Kozak, C.A., et al. Mamm. Genome 7(2):164-165(1996)

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$ 80.00
Cat# BP14271b
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