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M Mlkl Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9D2Y4
Clone Names 110316274
Peptide ID 110316274
Additional Information
Gene ID 74568
Other Names Mixed lineage kinase domain-like protein, Mlkl {ECO:0000312|EMBL:AAH237551, ECO:0000312|MGI:MGI:1921818}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mlkl {ECO:0000312|EMBL:AAH23755.1, ECO:0000312|MGI:MGI:1921818}
Function Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Cellular Location Cytoplasm. Cell membrane. Note=Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction.
Tissue Location Highly expressed in thymus, colon, intestine, liver, spleen and lung. Expressed at much lower level in skeletal muscle, heart and kidney. Not detected in brain
Research Areas
Citations (0)

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The protein kinase domain is predicted to be catalytically inactive. Molecular function: protein binding. There are two isoforms.


Bisson, N., et al. Cell Cycle 7(7):909-916(2008)

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$ 80.00
Cat# BP14272b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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