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TEAD3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q99594
Clone Names 110330009
Peptide ID 110330009
Additional Information
Gene ID 7005
Other Names Transcriptional enhancer factor TEF-5, DTEF-1, TEA domain family member 3, TEAD-3, TEAD3, TEAD5, TEF5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TEAD3
Synonyms TEAD5, TEF5
Function Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
Cellular Location Nucleus.
Tissue Location Preferentially expressed in the placenta.
Research Areas
Citations (0)

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This gene product is a member of the transcriptionalenhancer factor (TEF) family of transcription factors, whichcontain the TEA/ATTS DNA-binding domain. It is predominantlyexpressed in the placenta and is involved in the transactivation ofthe chorionic somatomammotropin-B gene enhancer. Translation ofthis protein is initiated at a non-AUG (AUA) start codon. [providedby RefSeq].


Zhang, H., et al. J. Biol. Chem. 284(20):13355-13362(2009)Zhao, B., et al. Genes Dev. 22(14):1962-1971(2008)Peng, L., et al. Mol. Endocrinol. 18(8):2049-2060(2004)Mungall, A.J., et al. Nature 425(6960):805-811(2003)Maeda, T., et al. J. Biol. Chem. 277(27):24346-24352(2002)

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$ 80.00
Cat# BP14305a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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