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ING1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UK53
Clone Names 100430269
Peptide ID 100430269
Additional Information
Gene ID 3621
Other Names Inhibitor of growth protein 1, ING1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ING1
Function Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
Cellular Location Nucleus.
Tissue Location Isoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines
Research Areas
Citations (0)

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This gene encodes a tumor suppressor protein that caninduce cell growth arrest and apoptosis. The encoded protein is anuclear protein that physically interacts with the tumor suppressorprotein TP53 and is a component of the p53 signaling pathway.Reduced expression and rearrangement of this gene have beendetected in various cancers. Multiple alternatively splicedtranscript variants encoding distinct isoforms have been reported.


Zhu, Z., et al. Hepatology 49(2):504-512(2009)Sayan, B., et al. Hybridoma (Larchmt) (2009) In press :Tallen, G., et al. Oncol. Res. 18 (2-3), 95-105 (2009) :Halaschek-Wiener, J., et al. PLoS ONE 4 (8), E6641 (2009) :Han, X., et al. Nat. Cell Biol. 10(11):1333-1340(2008)

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$ 80.00
Cat# BP14335a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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