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TAC3 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9UHF0 |
|---|---|
| Clone Names | 100517016 |
| Gene ID | 6866 |
|---|---|
| Other Names | Tachykinin-3, ZNEUROK1, Neurokinin-B, NKB, Neuromedin-K, TAC3, NKNB |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TAC3 |
|---|---|
| Synonyms | NKNB |
| Function | Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles (By similarity). Is a critical central regulator of gonadal function. |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the tachykinin family ofsecreted neuropeptides. The encoded protein is primarily expressedin the central and peripheral nervous system and functions as aneurotransmitter. This protein is the ligand for the neurokinin-3receptor. This protein is also expressed in the outersyncytiotrophoblast of the placenta and may be associated withpregnancy-induced hypertension and pre-eclampsia. Mutations in thisgene are associated with normosmic hypogonadotropic hypogonadism.Alternate splicing results in multiple transcript variants.
References
Klassert, T.E., et al. J. Neuroimmunol. 227 (1-2), 202-207 (2010) :Hrabovszky, E., et al. Eur. J. Neurosci. 31(11):1984-1998(2010)Gianetti, E., et al. J. Clin. Endocrinol. Metab. 95(6):2857-2867(2010)Young, J., et al. J. Clin. Endocrinol. Metab. 95(5):2287-2295(2010)Semple, R.K., et al. Front Horm Res 39, 133-141 (2010) :
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