DPPA4 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q7L190 |
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Clone Names | 70716010 |
Gene ID | 55211 |
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Other Names | Developmental pluripotency-associated protein 4, DPPA4 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP1438a was selected from the N-term region of human DPPA4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DPPA4 |
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Function | May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic cells into a primitive ectoderm lineage. |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q8CCG4}. Note=Associated with transcriptionally active chromatin {ECO:0000250|UniProtKB:Q8CCG4} |
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Provided below are standard protocols that you may find useful for product applications.
Background
DppA4 is a member of the Dppa family of developmental pluripotency associated transcription factors. Dppa4 is a target of Oct4, Sox2 and Nanog. It may play a role in maintaining cell pluripotentiality.
References
Bortvin,A., Development 130 (8), 1673-1680 (2003
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