|Other Names||Serine/threonine-protein phosphatase with EF-hands 2, PPEF-2, PPEF2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission.|
|Cellular Location||Cytoplasm. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment Note=Localized to photoreceptors, PPEF-2(L) is at least 2 fold more abundant in rod inner segments than in the outer segments|
|Tissue Location||Retinal specific.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the serine/threonine proteinphosphatase with EF-hand motif family. The protein contains aprotein phosphatase catalytic domain, and at least two EF-handcalcium-binding motifs in its C terminus. Although its substrate(s)is unknown, the encoded protein, which is expressed specifically inphotoreceptors and the pineal, has been suggested to play a role inthe visual system. This gene shares high sequence similarity withthe Drosophila retinal degeneration C (rdgC) gene. [provided byRefSeq].
Kutuzov, M.A., et al. Biochem. Biophys. Res. Commun. 293(3):1047-1052(2002)Ramulu, P., et al. Mol. Cell. Biol. 21(24):8605-8614(2001)Sherman, P.M., et al. Proc. Natl. Acad. Sci. U.S.A. 94(21):11639-11644(1997)
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