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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   HNMT Antibody (C-term) Blocking Peptide   

HNMT Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P50135
Clone Names 70319140
Peptide ID 70319140
Additional Information
Gene ID 3176
Other Names Histamine N-methyltransferase, HMT, HNMT
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1442b was selected from the C-term region of human HNMT. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalianbrain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.


Aksoy, S., et al., Biochem. Biophys. Res. Commun. 219(2):548-554 (1996).

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$ 80.00
Cat# BP1442b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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