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SPAK (STK39) Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9UEW8
Clone Names 70319128
Peptide ID 70319128
Additional Information
Gene ID 27347
Other Names STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1448b was selected from the C-term region of human STK39. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name STK39
Synonyms SPAK
Function May act as a mediator of stress-activated signals.
Cellular Location Cytoplasm. Nucleus. Note=Nucleus when caspase-cleaved.
Tissue Location Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis
Research Areas
Citations (0)

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STK39 is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.


Dowd, B.F., et al., J. Biol. Chem. 278(30):27347-27353 (2003).Johnston, A.M., et al., Oncogene 19(37):4290-4297 (2000).

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$ 80.00
Cat# BP1448b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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