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COL1A1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P02452
Clone Names 100427029
Peptide ID 100427029
Additional Information
Gene ID 1277
Other Names Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name COL1A1
Function Type I collagen is a member of group I collagen (fibrillar forming collagen).
Cellular Location Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}
Tissue Location Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite
Research Areas
Citations (0)

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This gene encodes the pro-alpha1 chains of type I collagenwhose triple helix comprises two alpha1 chains and one alpha2chain. Type I is a fibril-forming collagen found in most connectivetissues and is abundant in bone, cornea, dermis and tendon.Mutations in this gene are associated with osteogenesis imperfectatypes I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlossyndrome Classical type, Caffey Disease and idiopathicosteoporosis. Reciprocal translocations between chromosomes 17 and22, where this gene and the gene for platelet-derived growth factorbeta are located, are associated with a particular type of skintumor called dermatofibrosarcoma protuberans, resulting fromunregulated expression of the growth factor. Two transcripts,resulting from the use of alternate polyadenylation signals, havebeen identified for this gene. [provided by R. Dalgleish].


Blades, H.Z., et al. Bone 47(5):989-994(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Jin, H., et al. Osteoporos Int (2010) In press :Szczesny, G., et al. Arch Orthop Trauma Surg (2010) In press :Cheung, M.S., et al. J. Bone Miner. Res. (2010) In press :

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$ 80.00
Cat# BP14490b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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