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B3GALT2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O43825
Clone Names 100324207
Peptide ID 100324207
Additional Information
Gene ID 8707
Other Names Beta-1, 3-galactosyltransferase 2, Beta-1, 3-GalTase 2, Beta3Gal-T2, Beta3GalT2, 241-, UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2, B3GALT2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name B3GALT2
Function Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Detected in heart and brain.
Research Areas
Citations (0)

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This gene is a member of thebeta-1,3-galactosyltransferase (beta3GalT) gene family. This familyencodes type II membrane-bound glycoproteins with diverse enzymaticfunctions using different donor substrates (UDP-galactose andUDP-N-acetylglucosamine) and different acceptor sugars(N-acetylglucosamine, galactose, N-acetylgalactosamine). Thebeta3GalT genes are distantly related to the Drosophila Brainiacgene and have the protein coding sequence contained in a singleexon. The beta3GalT proteins also contain conserved sequences notfound in the beta4GalT or alpha3GalT proteins. The carbohydratechains synthesized by these enzymes are designated as type 1,whereas beta4GalT enzymes synthesize type 2 carbohydrate chains.The ratio of type 1:type 2 chains changes during embryogenesis. Bysequence similarity, the beta3GalT genes fall into at least twogroups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3,beta3GalT5). This gene encodes a protein that functions in N-linkedglycoprotein glycosylation and shows strict donor substratespecificity for UDP-galactose.


Lamesch, P., et al. Genomics 89(3):307-315(2007)Sood, R., et al. Genomics 73(2):211-222(2001)Amado, M., et al. Biochim. Biophys. Acta 1473(1):35-53(1999)Amado, M., et al. J. Biol. Chem. 273(21):12770-12778(1998)Kolbinger, F., et al. J. Biol. Chem. 273(1):433-440(1998)

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$ 80.00
Cat# BP14494b
Availability: In Stock
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