|Other Names||p53 apoptosis effector related to PMP-22, Keratinocyte-associated protein 1, KCP-1, P53-induced protein PIGPC1, Transmembrane protein THW, PERP, KCP1, KRTCAP1, PIGPC1, THW|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||KCP1, KRTCAP1, PIGPC1, THW|
|Function||Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).|
|Cellular Location||Cell junction, desmosome. Cell membrane; Multi-pass membrane protein Note=Associated with desmosomes.|
|Tissue Location||Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts|
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Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Yarden, R.I., et al. Mol. Carcinog. 49(6):545-555(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Beaudry, V.G., et al. Am. J. Med. Genet. A 149A (9), 1952-1957 (2009) :
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