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PERP Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96FX8
Clone Names 100517161
Additional Information
Gene ID 64065
Other Names p53 apoptosis effector related to PMP-22, Keratinocyte-associated protein 1, KCP-1, P53-induced protein PIGPC1, Transmembrane protein THW, PERP, KCP1, KRTCAP1, PIGPC1, THW
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PERP
Function Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly.
Cellular Location Cell junction, desmosome {ECO:0000250|UniProtKB:Q9JK95}. Cell membrane; Multi-pass membrane protein. Note=Associated with desmosomes (By similarity). Colocalizes with KRT14 in the cell membrane (PubMed:31898316). {ECO:0000250|UniProtKB:Q9JK95, ECO:0000269|PubMed:31898316}
Tissue Location Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts
Research Areas
Citations (0)
citation

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Background

Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Yarden, R.I., et al. Mol. Carcinog. 49(6):545-555(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Beaudry, V.G., et al. Am. J. Med. Genet. A 149A (9), 1952-1957 (2009) :

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$ 277.78
Cat# BP14508b
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Availability: 2 weeks
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