|Other Names||Transcriptional repressor p66-beta, GATA zinc finger domain-containing protein 2B, p66/p68, GATAD2B, KIAA1150|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development.|
|Cellular Location||Nucleus speckle. Note=Speckled nuclear localization requires both CR1 and CR2 regions|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
GATAD2B has transcriptional repressor activity. Targets MBD3 to discrete loci in the nucleus.
Ichikawa, S., et al. J. Bone Miner. Res. 23(10):1680-1688(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)Brackertz, M., et al. Nucleic Acids Res. 34(2):397-406(2006)
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