|Other Names||Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BP, AATK, AATYK, KIAA0641, LMR1, LMTK1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||AATYK, KIAA0641, LMR1, LMTK1|
|Function||May be involved in neuronal differentiation.|
|Cellular Location||Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Predominantly perinuclear|
|Tissue Location||Expressed in brain.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene contains a tyrosinekinase domain at the N-terminus and a proline-rich domain at theC-terminus. This gene is induced during apoptosis, and expressionof this gene may be a necessary pre-requisite for the induction ofgrowth arrest and/or apoptosis of myeloid precursor cells. Thisgene has been shown to produce neuronal differentiation in aneuroblastoma cell line.
Tomomura, M., et al. Neuroscience 148(2):510-521(2007)Lee, S., et al. Oncol. Rep. 16(4):747-754(2006)Honma, N., et al. Biochem. Biophys. Res. Commun. 310(2):398-404(2003)Tomomura, M., et al. Brain Res. Mol. Brain Res. 112 (1-2), 103-112 (2003) :Tomomura, M., et al. Oncogene 20(9):1022-1032(2001)
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