AATK Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6ZMQ8 |
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Clone Names | 100525003 |
Gene ID | 9625 |
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Other Names | Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BP, AATK, AATYK, KIAA0641, LMR1, LMTK1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | AATK |
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Synonyms | AATYK, KIAA0641, LMR1, LMTK1 |
Function | May be involved in neuronal differentiation. |
Cellular Location | Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Predominantly perinuclear |
Tissue Location | Expressed in brain.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene contains a tyrosinekinase domain at the N-terminus and a proline-rich domain at theC-terminus. This gene is induced during apoptosis, and expressionof this gene may be a necessary pre-requisite for the induction ofgrowth arrest and/or apoptosis of myeloid precursor cells. Thisgene has been shown to produce neuronal differentiation in aneuroblastoma cell line.
References
Tomomura, M., et al. Neuroscience 148(2):510-521(2007)Lee, S., et al. Oncol. Rep. 16(4):747-754(2006)Honma, N., et al. Biochem. Biophys. Res. Commun. 310(2):398-404(2003)Tomomura, M., et al. Brain Res. Mol. Brain Res. 112 (1-2), 103-112 (2003) :Tomomura, M., et al. Oncogene 20(9):1022-1032(2001)
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