|Other Names||Solute carrier family 15 member 1, Intestinal H(+)/peptide cotransporter, Oligopeptide transporter, small intestine isoform, Peptide transporter 1, SLC15A1, PEPT1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an intestinal hydrogen peptidecotransporter that is a member of the solute carrier family 15. Theencoded protein is localized to the brush border membrane of theintestinal epithelium and mediates the uptake of di- andtripeptides from the lumen into the enterocytes. This protein playsan important role in the uptake and digestion of dietary proteins.This protein also facilitates the absorption of numerouspeptidomimetic drugs.
Dalmasso, G., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (3), G687-G696 (2010) :Pieri, M., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (1), G136-G143 (2010) :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Geissler, S., et al. J. Agric. Food Chem. 58(4):2543-2547(2010)Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
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