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HAT1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O14929
Clone Names 100507143
Peptide ID 100507143
Additional Information
Gene ID 8520
Other Names Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase 1, HAT1, KAT1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HAT1
Synonyms KAT1
Function Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.
Cellular Location Isoform A: Nucleus matrix.
Research Areas
Citations (0)

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The protein encoded by this gene is a type B histoneacetyltransferase (HAT) that is involved in the rapid acetylationof newly synthesized cytoplasmic histones, which are in turnimported into the nucleus for de novo deposition onto nascent DNAchains. Histone acetylation, particularly of histone H4, plays animportant role in replication-dependent chromatin assembly.Specifically, this HAT can acetylate soluble but not nucleosomalhistone H4 at lysines 5 and 12, and to a lesser degree, histone H2Aat lysine 5. Alternatively spliced transcript variants have beenidentified for this gene.


Saade, E., et al. Proteomics 9(21):4934-4943(2009)Miyamoto, N., et al. J. Biol. Chem. 283(26):18218-18226(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Benson, L.J., et al. J. Biol. Chem. 282(2):836-842(2007)

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$ 80.00
Cat# BP14563a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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