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PGF Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P49763
Clone Names 100507211
Peptide ID 100507211
Additional Information
Gene ID 5228
Other Names Placenta growth factor, PlGF, PGF, PGFL, PLGF
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PGF
Synonyms PGFL, PLGF
Function Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Cellular Location Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin
Tissue Location While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas
Research Areas
Citations (0)

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The PGF gene encodes placenta growth factor, a homolog ofvascular endothelial growth factor (VEGFA; MIM 192240), thatselectively binds to VEGFR1 (FLT1; MIM 165070) and is involved inangiogenesis (Fischer et al., 2007 [PubMed 17981115]; Bais et al.,2010 [PubMed 20371352]).


Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Cowans, N.J., et al. Prenat. Diagn. 30(6):565-570(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :Andersson, M.K., et al. BMC Cancer 10, 249 (2010) :Pan, P., et al. BMC Cell Biol. 11, 36 (2010) :

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$ 80.00
Cat# BP14578c
(40 western blots)
Availability: In Stock
Bulk Size
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