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FST Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P19883
Clone Names 100507255
Peptide ID 100507255
Additional Information
Gene ID 10468
Other Names Follistatin, FS, Activin-binding protein, FST
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FST
Function Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
Cellular Location Secreted.
Tissue Location Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid
Research Areas
Citations (0)

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Background

Follistatin is a single-chain gonadal protein thatspecifically inhibits follicle-stimulating hormone release. Thesingle FST gene encodes two isoforms, FST317 and FST344 containing317 and 344 amino acids respectively, resulting from alternativesplicing of the precursor mRNA. In a study in which 37 candidategenes were tested for linkage and association with polycystic ovarysyndrome (PCOS) or hyperandrogenemia in 150 families, evidence wasfound for linkage between PCOS and follistatin. [provided byRefSeq].

References

Chen, M.J., et al. Hum. Reprod. 25(3):779-785(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :Fajardo, M., et al. Clin. Orthop. Relat. Res. 467(12):3071-3078(2009)Bloise, E., et al. BMC Cancer 9, 320 (2009) :

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$ 80.00
Cat# BP14597b
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