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PSMD1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q99460
Clone Names 100507264
Peptide ID 100507264
Additional Information
Gene ID 5707
Other Names 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome regulatory subunit RPN2, 26S proteasome regulatory subunit S1, 26S proteasome subunit p112, PSMD1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSMD1
Function Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Research Areas
Citations (0)

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The 26S proteasome is a multicatalytic proteinase complexwith a highly ordered structure composed of 2 complexes, a 20S coreand a 19S regulator. The 20S core is composed of 4 rings of 28non-identical subunits; 2 rings are composed of 7 alpha subunitsand 2 rings are composed of 7 beta subunits. The 19S regulator iscomposed of a base, which contains 6 ATPase subunits and 2non-ATPase subunits, and a lid, which contains up to 10 non-ATPasesubunits. Proteasomes are distributed throughout eukaryotic cellsat a high concentration and cleave peptides in anATP/ubiquitin-dependent process in a non-lysosomal pathway. Anessential function of a modified proteasome, the immunoproteasome,is the processing of class I MHC peptides. This gene encodes thelargest non-ATPase subunit of the 19S regulator lid, which isresponsible for substrate recognition and binding. Alternativelyspliced transcript variants have been found for this gene.[providedby RefSeq].


Bailey, S.D., et al. Diabetes Care (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)da Fonseca, P.C., et al. J. Biol. Chem. 283(34):23305-23314(2008)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

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$ 80.00
Cat# BP14601a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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