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Mouse Ddr2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q62371
Clone Names 110316128
Peptide ID 110316128
Additional Information
Gene ID 18214
Other Names Discoidin domain-containing receptor 2, Discoidin domain receptor 2, CD167 antigen-like family member B, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10, CD167b, Ddr2, Ntrkr3, Tkt, Tyro10
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ddr2
Synonyms Ntrkr3, Tkt, Tyro10
Function Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Widely expressed. Detected in lung, ovary, skin and in testis Leydig cells (at protein level). Widely expressed. Detected at high levels in heart, lung, skeletal muscle, central nervous system (CNS) and kidney, and at lower levels in brain and testis. Detected in chondrocytes in tibia growth plates of young mice.
Research Areas
Citations (0)

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This tyrosine kinase receptor for fibrillar collagen mediates fibroblast migration and proliferation. Contributes to cutaneous wound healing.


Xu, L., et al. Arthritis Rheum. 62(9):2736-2744(2010)Sivakumar, L., et al. Biomaterials 31(18):4802-4808(2010)Flynn, L.A., et al. J. Mol. Biol. 395(3):533-543(2010)Kano, K., et al. Mol. Reprod. Dev. 77(1):29-37(2010)Matsumura, H., et al. Physiol. Genomics 39(2):120-129(2009)

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$ 80.00
Cat# BP14616b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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