|Other Names||Olfactory marker protein, Olfactory neuronal-specific protein, OMP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May act as a modulator of the olfactory signal- transduction cascade.|
|Tissue Location||Uniquely associated with mature olfactory receptor neurons|
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Olfactory marker protein is uniquely associated with themature olfactory receptor neurons in many vertebrate species fromfish to man. The OMP gene structure and protein sequence arehighly conserved between mouse, rat and human. Results of themouse knockout studies show that OMP-null mice are compromised intheir ability to respond to odor stimuli, and that OMP represents anovel modulatory component of the odor detection/signaltransduction cascade.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Behrens, M., et al. J. Neurochem. 86(5):1289-1296(2003)Baldisseri, D.M., et al. J. Mol. Biol. 319(3):823-837(2002)
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